dear brothers: The Greek word adelphoi is a traditional term of affection for family members, both male and female.
the hardships we encountered in the province of Asia: The trouble faced in the province of Asia is hard to pinpoint. One suggestion is the riot in Ephesus (Acts 19:23–41). Another is that Paul was tried in a civil court and faced possible execution in Ephesus (2 Corinthians 1:9; see 1 Corinthians 15:32). It is less likely that he suffered a severe life-threatening illness. Paul often faced mortal danger (2 Corinthians 1:10; see also 4:10–12; 6:9; 11:23), but he was wonderfully rescued by divine help (1:11).